Testing for Infection
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AcuDart Home Test
At-home initial screen (new tick bite, no access to a clinic)
At-Home Lyme Antibody Test – broad Borrelia antibody screen for early immune response.
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IgeneX
Best for: Early and evolving infections
Lyme ImmunoBlot IgM & IgG – more sensitive than standard Western Blot for early Lyme.
PCR Panel – detects Borrelia burgdorferi, B. miyamotoi, Babesia microti, Bartonella henselae, Anaplasma phagocytophilum DNA.
Tick-Borne Relapsing Fever ImmunoBlot – helpful if traditional Lyme tests are negative but symptoms persist.
Babesia FISH – detects active parasitemia (useful early).
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Galaxy Diagnostics
Bartonella or Rickettsia soon after exposure
Bartonella ePCR™ – multi-draw PCR that can pick up bacteremia in the early phase.
Rickettsia PCR Panel – if patient presents with acute fever and rash.
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Vibrant Wellness
Broad antibody and peptide-based screen
Lyme Disease Panel (Borrelia species–specific peptides)
Co-Infection Panel (Bartonella, Babesia, Ehrlichia, Anaplasma, Rickettsia, etc.)
Tickborne 2.0 or Total Tickborne Panel (covers multiple vector pathogens)
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T Lab Inc
Early-stage microscopic confirmation
Borrelia PCR + Microscopy Combo – detects spirochetes directly from blood or tissue.
Co-Infection PCR Panel – screens Babesia, Bartonella, Ehrlichia, and Rickettsia.
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Standard of Care Core Tests
(often insurance-covered, first-line for new infections):
Antibody tests (ELISA, ImmunoBlot) may stay negative for the first 2–4 weeks. PCR or FISH testing, combined with clinical evaluation and early treatment, improves early detection.
KeyTests: ELISA:ScreensforBorreliaantibodies(IgM,IgG)
Western Blot / ImmunoBlot: Confirms ELISA results
PCR: Detects Borrelia DNA in blood, skin, or CSF
CBC / CMP / ESR / CRP: Assess inflammation and organ function
Note: Vector-borne illnesses are often clinical diagnoses, as tests may be serum-negative and difficult to detect.
Testing For Late Stage Co Morbidities
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Vibrant's "Neuro Zoomer" tests for Inflammation
The Neural Zoomer Plus is a blood test assessing immune reactivity to neurological antigens linked to neuroinflammation, cognitive decline, and autoimmune brain disorders. It offers detailed analysis of nervous system health to identify immune triggers and guide targeted neurological care.
Measures:
24 Neurological Autoimmunity & Inflammation Markers
10 Peripheral & Neuromuscular Disorder Markers
13 Blood-Brain Barrier & Nervous System Integrity Markers
7 Infection-Associated Autoimmune Reactivity Markers
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Moleculara Biosciences "Autoimmune Brain Panel" Tests for Antibodies to the Brain
The Panel measures autoimmune antibodies against brain targets like Dopamine D1/D2 receptors, Lysoganglioside, and Tubulin, linked to neuropsychiatric symptoms such as tics, OCD-like behaviors, ADHD, anxiety, and depression. Elevated levels suggest symptoms may stem from infection-triggered autoimmune processes, aiding treatment decisions. Up to 60% of patients with neurological and psychiatric disorders worldwide are treatment-resistant, possibly due to undiagnosed infection-driven immune dysfunction from diseases like Lyme & Coinfection.
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Religen's "FRAT" Test
FRAT® (Folate Receptor Antibody Test) detects Folate Receptor Autoantibodies (FRAs) in blood. In a study of 47 PANS/PANDAS patients, 63.8% tested positive. Infection-induced PANS is a neuropsychiatric condition linked to vector illness. FRAT® uniquely detects both blocking and binding FRAs, as noted in the New England Journal of Medicine. FRA presence disrupts folate (vitamin B9) transport to the brain and CSF, affecting growth and neurological function.
FRAs are linked to Cerebral Folate Deficiency Syndrome, Autism, Depression, Schizophrenia, and other neuropsychiatric disorders. Presence in late vector borne illness is suspected but not yet studied.
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Religen's "Mitoswab" Detects Mitochondrial Health
Mitochondrial testing may be beneficial for individuals experiencing chronic health concerns affecting three or more body systems: This could include combinations of symptoms such as muscle weakness, digestive issues, and neurological/behavioral problems.
Chronic infections and mitochondrial dysfunction are closely linked in a two-way relationship, contributing to conditions like encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID. Pathogens like Vector Illness can directly damage mitochondria and manipulate cell metabolism for their benefit.
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Standard of Care Testing
Neuroimaging (MRI, SPECT): Assesses brain and nerve changes caused by infection.
EEG or nerve studies: Evaluate brain and nerve function.
Comorbidity & Systemic Testing: HPA axis / adrenal function: Cortisol, ACTH, and related hormone panels to check stress-response system.
Cardiac evaluation: ECG, echocardiogram, or troponin tests if heart involvement is suspected.
Inflammatory markers: ESR, CRP, Immunoglobulin and cytokine panels to assess immune competence & systemic inflammation.
Autoimmune panels: ANA, ENA, anti-neuronal antibodies to rule out overlapping autoimmune conditions.
Why this matters: Lyme can affect multiple systems, and chronic or late-stage infection may trigger or worsen inflammation, autoimmune reactions, hormonal imbalance, or heart issues. Comprehensive testing helps doctors tailor treatment to your whole-body health, not just the infection.

